Bryan De La Cruz was born December 16, 1996, in Santo Domingo Este, Dominican Republic. He is an outfielder in the MLB.
De La Cruz signed with the Houston Astros organization as an international free agent on September 24, 2013, for a $170,000 signing bonus. He spent his professional debut season with the Dominican Summer League Astros, hitting 262/.387/.317/.704 with 1 home run and 22 RBI. His 2015 season was spent with the Gulf Coast League Astros, hitting .242/.313/.268/.582 with 12 RBI. He split the 2016 season between the Greeneville Astros and the Tri-City ValleyCats, hitting a combined .239/.331/.396/.727 with 3 home runs and 18 RBI. He split the 2017 season between Tri-City, the Quad Cities River Bandits and the Corpus Christi Hooks, hitting a combined .244/.290/.335/.625 with 2 home runs and 21 RBI. He split the 2018 season between Quad Cities and the Buies Creek Astros, hitting a combined .289/.367/.375/.742 with 2 home runs and 62 RBI. De La Cruz split the 2019 season between the Fayetteville Woodpeckers and Corpus Christi, hitting a combined .280/.340/.428/.768 with 8 home runs and 43 RBI. He opened the 2021 season with the Sugar Land Skeeters, hitting .324/.362/.518/.880 with 12 home runs and 50 RBI over 66 games with them.
On July 28, 2021, De La Cruz and Austin Pruitt were traded to the Miami Marlins in exchange for Yimi García. On July 30, Miami selected his contract and promoted him to the major leagues. He made his MLB debut that night against the New York Yankees.
De La Cruz made the Marlins Opening Day roster for the 2022 season.